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A Peek At Our Work
Structure of PvHK tetramers as resolved by cryoEM
Glucose-bound NfGlck (PDB:6DA0): Provided by Isabelle Phan
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Naegleria pursues a meal (bacteria)
Gene expression changes in response to glucose: Data generated by RNAseq analysis of parasite response to glucose
Hexose transporter localization in trypanosomes: Procyclic form African trypanosomes expressing eYFP-tagged hexose transporters (THT1 or 2) or eYFP alone.
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NfGlck activity with various hexoses (published in AAC, 2018)
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Response of N. fowleri to various carbon sources (published in AAC, 2018)
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Naegleria fowleri, a pathogenic free-living amoeba (the “brain eater”) imaged by labeling with endoc
IFA of HATbP3L. A. Parasites expressing HATbP3L were fixed, permeabilized and stained with antibodi
Distribution of eYFP.Ngt (a glucose transporter) in African trypanosomes.
Balamuthia mandrillaris, a pathogenic free-living amoeba we study
African trypanosome with glycosomes labeled using PTS2-eYFP
African trypanosomes, with green (anti-TbHK2 antibody), blue (DAPI), and red (anti-paraflagellar rod): The pink in the bottom right is basal body marker
IF with Pex13.1 (green) and Pex14 (magenta) shown. These are key components of the glycosome import complex
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